Sulphonamides for Sonne Dysentery

The Sulphonamides in Bacillary Dysentery

The Use of Sulfaguanidine for Prophylaxis in Sonne Bacillary Dysentery, and in the Control of the Carrier State *

In an earlier paper the therapeutic effectiveness of sulfathiazole used during the acute stages of Sonne bacillary dysentery was demonstrated.5 However, it was shown also that sulfonamide therapy did not curtail the period during which the Sonne organism could be recovered by rectal cultures. Actually, there appeared to be statistical evidence that this period was prolonged when compared with u...

Sulphonamides: A Pharmaceutical Review

Sulphonamides are the first effective chemotherapeutic agents used for bacterial infection in humans. Sulfonamides have a wide range of pharmacological activities such as Oral hypoglycemic, antileprotic, anti epileptic, anti-hypertensive, anti-bacterial, anti-protozoal, anti-fungal, anti retroviral, anti cancer, antiinflammatory, and used as diuretic. This review consists of a discussion on the...

Sulphonamides in Undulant Fever

Further studies on the antibiotic resistance of Shigella sonnei. II. The acquisition of transferable antibiotic resistance in vivo.

Previous studies on the epidemiology of Sonne dysentery in the London area (Davies, 1954; Farrant & Tomlinson, 1966) described the trend towards an increased frequency of strains of Shigella sonnei resistant to sulphonamides and later to streptomycin and tetracycline. It seemed relevant to continue and extend these observations. Recent work on the transfer of antibiotic resistance between organ...